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We first tested the therapeutic relevance of GLP-1(2836) in vivo in 10- to 12-week-old male C57BL/6J mice subjected to permanent ligation of the left anterior descending (LAD) artery following 14 days of s.c

Relatively common side effects Internal bleeding or itching at the injection site, diarrhea, constipation, headache Severe side effects hypoglycemia, pancreatitis, bowel obstruction, palpitations *Although GLP-1 alone rarely causes hypoglycemia, it has been reported that combined use with insulin or oral hypoglycemic agents can cause severe hypoglycemia

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