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Because of the close relationship between risk factors in human metabolism and the expression of GLP-1R in the musculoskeletal system, GLP-1RAs may have great potential in the treatment of many diseases of the musculoskeletal system

Hernandez, A

Scientific References TripleHormone-Receptor Agonist Retatrutide for Obesity (Jastreboff et al.)

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Given that GLP-1R agonists have superior weight loss effects and good safety, some of its products have been officially approved by FDA for chronic weight management of obese or overweight adults

The medication is currently being studied in the TRIUMPH Phase 3 clinical trial program, which is typically the final stage of testing before companies apply for FDA approval