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Both medications cause some lean mass loss, but the ratio of fat loss to lean mass loss appears to favor tirzepatide based on available body composition data from the SURMOUNT trials

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Rhesus macaques that were administered a high inoculum of SARS-CoV-2 by nasal, tracheal, ocular and oral routes had increased temperatures and respiratory rates for 1 day, and reduced appetite and dehydration for 916 days 122

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