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The effects of compound 102 on luciferase activity were tested using HEK293T cells expressing wild type luciferase

The protocols for enzyme activity assessment were adopted from the methods outlined by Li et al

All suspected adverse reactions should also be reported to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk

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The method of any one of embodiments 118-121, wherein the medium chain fatty acids are caproic acid (hexanoic acid), enanthic acid (heptanoic acid), caprylic acid (octanoic acid), pelargonic acid (nonanoic acid), capric acid (decanoic acid), undecylenic acid (undec-10-enoic acid), lauric acid (dodecanoic acid), or any combinations thereof

Niacinamide rounds out the formula by refining pores and evening skin tone for a radiant complexion