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Weight Loss and Obesity Treatment In addition to their role in managing type 2 diabetes, GLP-1 agonists have gained significant attention for their potential in promoting weight loss and treating obesity

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Fusco J et al (2017): GLP-1/Exendin-4 induces -cell proliferation via the epidermal growth factor receptor

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More serious but less common safety considerations observed across this drug class include a potential risk of pancreatitis, gallbladder-related conditions (such as gallstones/cholelithiasis), and based on animal studies a theoretical concern regarding thyroid C-cell tumours, though this has not been confirmed in human trials

doi: 10.1016/j.phrs.2021.105782 80 CantiniGMannucciELuconiM