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Additionally, increased frequencies of diabetes mellitus, high blood pressure, kidney pathologies, coronary artery disease and raised serum lipids were identified [20]

But researchers caution that the study, though large, was not the sort of controlled clinical trial needed to confirm that GLP-1 drugs offer a safe and effective way to treat addiction

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With normalisation of glycated haemoglobin levels and weight losses around 1525%, therapeutic goals that were previously unrealistic are now within reach, and clinical trials have documented that these effects are associated with reduced risk of cardiovascular events and premature mortality

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