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Despite the considerable cost, the evidence presented to the NICE committee suggests this medicine is a cost-effective use of NHS resources for some patients

1 People with plaque erosion have better outcomes than those with plaque rupture, possibly because they have a lower overall atherosclerosis burden and fewer traditional cardiovascular risk factors

The 2005 Jett Endocrinology paper characterised the parent hGRF(1-29)-albumin bioconjugate as a GRF-receptor agonist on anterior pituitary somatotroph cells (PMID 15817669)

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Effect of Subcutaneous Tirzepatide vs Placebo added to titrated insulin glargine on Glycemic Control in patients with type 2 diabetes: the SURPASS-5 Randomized Clinical Trial