Practical Considerations for Prescribers When planning treatment strategies in 2026, its important to address the side effects of metformin, its affordability, and how it compares to newer medications in patient-specific contexts
GLP-1 receptor agonists available in the UK include: Semaglutide (Ozempic, Wegovy, Rybelsus) Dulaglutide (Trulicity) Liraglutide (Victoza, Saxenda) Exenatide (Byetta, Bydureon) These medications are administered either as subcutaneous injections (weekly or daily, depending on the formulation) or as oral tablets (Rybelsus)
For example, low glutathione levels can be a precursor for heart and fatty liver disease
Side effects such as glycosuria, hyperglycemia, diarrhea, polydipsia and polyuria have been observed in some species
Using glycolic acid and salicylic acid together can be beneficial but requires caution due to the increased risk of irritation
Nutrients 14:1637