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Presenting symptoms consist of persistent pain in upper abdomen and vomiting

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Severe vitamin E deficiency results mainly in neurological symptoms, including impaired balance and coordination (ataxia), injury to the sensory nerves (peripheral neuropathy), muscle weakness (myopathy), and damage to the retina of the eye (pigmented retinopathy)

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Most peptides exert their effects through a specific receptor or pathway that is present in limited tissue types