Funnel plot asymmetry and Eggers tests suggested potential small-study effects in some datasets (HDRS, BDI), raising concerns about publication bias
68 Detailed analysis suggests a multipronged effect of the changes in intestinal claudin-1 expression, including mucosal barrier properties (mucin-2 expression) and epithelial homeostasis
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Springer J, Scholz FR, Peiser C, Groneberg D, Fischer A: SMAD-signaling in chronic obstructive pulmonary disease: transcriptional down-regulation of inhibitory SMAD 6 and 7 by cigarette smoke