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Hurtado, Maria D., et al

Chronic hyperglycemia leads to advanced glycation end products, oxidative stress, and inflammation that damage the blood vessels supplying the penis

Tirzepatide has a half-life of about 5 days, meaning blood levels decrease by half every five days

This process begins with endothelial dysfunction, a critical event in the pathogenesis of atherosclerosis [64]

Investigations may include blood tests (HbA1c, lipid profile, morning total testosterone on two occasions if low, possibly SHBG and prolactin if indicated, thyroid function) and blood pressure measurement

Increased expression of Drosophila tetraspanin, Tsp68C, suppresses the abnormal proliferation of ytr-deficient and Ras/Raf-activated hemocytes