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doi:10.1016/S0891-5849(99)00177-X

and 2022ZD0213000 to F.Z.)

It is involved in the mechanisms of ferroptosis, necroptosis, and apoptosis across various cancer types, including metastatic melanoma, breast, prostate, and liver cancers, as well as Burkitts lymphoma and glioblastoma multiforme

Passaretti 1991

Deficiencies in these enzymes can lead to hemolytic anemia