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Changes in the expansion of polymorphonuclear precursors to granulocyte-colony stimulating factor (G-CSF) have been observed in elderly individuals [124], although responses to other stimulants like IL-3 and granulocytemacrophage colony stimulating factor (GM-CSF) remain unchanged, ensuring sufficient neutrophilia during infection [125, 126]

Acknowledgements The authors are thankful to Chinese Government Scholarship (CSC) and National Natural Science Foundation of China for supporting our study and Yasir Islam and Abdullah Ahmad for their comments and critical reading of the manuscript

PMC 2566617

Commitment to Regular and Comprehensive Care: Regular injections are essential for maintaining healthy levels and preventing recurrence