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3, Supplementary Table S3)

GHK-Cu is glycyl-L-histidyl-L-lysine complexed with copper(II)

p = 0.04) (Table 3)

When GLP-1 binds to GLP-1R on the surface of -cells, cAMP-dependent PKA is activated and subsequently activates the downstream signal PI3K, which inhibits apoptosis in islet -cells by blocking the expression of the pro-apoptotic protein Bax (Li et al., 2021) (Figure 4)

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