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References Mischley LK, Conley, KE, Shankland EG et al
An APOE-dependent molecular signature is commonly observed in AD-associated microglia
In a study of 643 cardiac patients who underwent coronary angiography in Germany, those who died of heart attacks had much lower glutathione peroxidase levels than those who survived.14 In the end, what this means is that if we don't have enough glutathione to neutralize damage to our arteries, we are at increased risk of heart and vascular disease events
In addition to the well-established extracellular GSH degradation mechanism, studies have shown an additional intracellular hydrolysis pathway for GSH degradation (47,48)
Advances in Experimental Medicine and Biology, vol 1311