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49 Elevated inflammatory factors in T2D such as IL-6 and interferon- (IFN-) cand bind to their receptors, activate JAK2/STAT3, subsequently upregulates the expression of suppressor of cytokine signaling 3 (SOCS3), which inhibit IRS-1 cascade

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Given that GPX4 deficiency leads directly to cell death 35 , we established stable GPX4 protein knockdown in Raji cells

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Glutathione: Coined the mother of all antioxidants, glutathione is the main antioxidant and detoxifier of every cell in your body (22)