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It means that the drug should be used only when the benefits outweigh the potential risks to the health of the woman and the fetus
References Liu R-M
Drug interactions Berberine may inhibit several cytochrome P450 enzymes (including CYP3A4, CYP2D6, and CYP2C9) and P-glycoprotein, potentially affecting the metabolism of numerous medications including statins, anticoagulants, antihypertensives, and immunosuppressants
Mechanism of Action of Melanotan Peptides Melanotan peptides interact with our bodys melanocortin system, which controls skin pigment production