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While the prescribing information for GLP-1 medications does not specifically list Crohn's disease as a contraindication, the Summary of Product Characteristics (SmPC) for these medicines does advise caution in patients with gastrointestinal disease and states they are not recommended in severe gastrointestinal disease

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doi: 10.1111/j.1750-3841.2012.02762.x 46 SawC

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Most vials maintain full potency for 28 days when stored at 28C (3646F), but storage mistakes can reduce effectiveness and increase waste

Caffeine, a major component of coffee, is a central nervous system stimulant that can impact various metabolic processes, including those related to antioxidant activity