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Comprehensive laboratory monitoring showed no clinically significant changes in vital signs, blood chemistry, or hormonal parameters
PPP intermediate products such as 6-phosphogluconate, ribulose-5P, sedoheptulose-7P, and glyceraldehide-3P were increased, and glucose-6P was decreased (Supplemental Figure 3B)
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For Research Use Only
Studies have highlighted that the conversion of glucose to lactate by cells constitutes a tightly regulated metabolic state, which may confer advantages during periods of heightened biosynthetic demand (29,30)