If mitochondria are damaged, adenine nucleotide transport protein (ANT) interacts with the translocase of inner mitochondria membrane 44 (TIM44) and prevents PINK1 from entering the TIM23 complex, while at the same time, mitochondrial outer membrane translocase 7 (TOM7) binds to the C-terminus of PINK1, causing PINK1 to remain on the outer mitochondrial membrane [30, 31]
In a study by Shen et al
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Moreover, mechanistic studies offer promising pathways, such as neurotrophin signaling, oxidative stress modulation, and inflammatory regulation, but are still primarily grounded in animal models
Peptide-Based Treatments for Diabetes semaglutide and other GLP-1 receptor agonists
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