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Cold Spring Harbor Perspectives in Biology, 6(1)

In this study, subjects were arbitrarily assigned to one of the sodium selenite (100 micrograms twice daily), pentoxifylline (600 mg twice daily), or placebo (twice daily) therapy groups for a duration of 6 months

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Huang, Y., Cohen, J

Key Takeaways Glutathione neutralizes acetaldehyde through glutathione S-transferase conjugation, reducing the toxic metabolite responsible for 6070% of hangover symptoms when dosed at 6001200mg before alcohol consumption