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doi: 10.1038/s41467-021-23111-1 113 GuerreiroR.WojtasA.BrasJ.CarrasquilloM.RogaevaE.MajounieE.et al

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The Hageman factor and complement and kinin systems are activated, which leads to collagen degradation and increases the permeability of cutaneous vessels (162)

He encouraged me to ask questions and he answered them all very well and thoroughly

In addition, high expression of Socs3 inhibited IL-6/STAT3 signaling and activation of downstream signaling pathways, thereby suppressing IL-6 levels and TH17 cell proliferation (Shi et al., 2016)