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doi: 10.1007/s10811-018-1501-7 73 WangW.ZhuJ.XuP.XuJ.LinX.HuangC.et al

The animal experiment results demonstrated that butyrate plays a key immunomodulatory role in SLE by targeting B cells through epigenetic mechanisms (156, 157)

Why receptor subtype work matters for interpretation A common question is which receptor subtype is doing the work. A 2025 mechanistic study investigated AMY receptor subtype dependence and reported that cagrilintides body weight lowering effects depended on AMY1R and AMY3R in their models, which provides a more concrete receptor anchored explanation than general appetite language

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