Urbancic KF, Pisasale D, Wight J, Trubiano JA (2018) Dapsone safety in hematology patients: pathways to optimizing Pneumocystis jirovecii pneumonia prophylaxis in hematology malignancy and transplant recipients
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Based on results from the SURMOUNT-OSA trial, investigating tirzepatide in OSA patients with obesity, Eli Lilly submitted a supplemental new drug application to the FDA in June seeking approval for OSA
The 624Mel cell line was slightly more responsive with ZIP scores of 15.4, 14.0, 13.4 in response to the same three drug combinations (Supplementary Table 5)
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These limited reports suggest good tolerability, though the small sample sizes, lack of standardized safety monitoring, and retrospective or uncontrolled study designs limit definitive safety conclusions