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Regular exercise also reduces systemic inflammation by lowering circulating levels of pro-inflammatory cytokines (e.g., TNF-, IL-6) and stimulating the release of anti-inflammatory myokines such as irisin and interleukin-15 from muscle, which promote lipid oxidation and vascular health (149)

By reducing oxidative stress in immune cells, it helps maintain their integrity and functionality, ensuring a robust immune response

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But it can also disrupt sleep patterns initially, especially if nausea or GI discomfort occurs at night

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