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Patients received once-weekly Ozempic 0.5mg or 1 mg, or placebo, in addition to standard of care

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For instance, myosteatosis impairs muscle health through both metabolic dysfunction and inflammation, while chronic low-grade inflammation negatively affects metabolic balance by inhibiting protein synthesis and increasing proteolysis via signaling pathways [39]

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Rilotumumab has also been evaluated in a phase II trial aiming to study its safety and efficacy in combination with bevacizumab (Avastin, Genentech, South San Francisco, California, USA) for the treatment of recurrent malignant glioma, showing no significant improvement and low tolerability [95]