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albicans , disrupting ARG83 ( CPAR2_400180 ) results in the inability to use proline as a nitrogen source 37 , and Uga3 ( CPAR2_200790 ) is required for using Gamma Amino-Butyric Acid (GABA) 37,45

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Two factors compound: drug exposure scales with body weight (lighter body = more drug per pound), and physiological response varies by metabolic and cardiovascular phenotype

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