The most frequently reported adverse effects of Zepbound are gastrointestinal in nature, consistent with the medication's mechanism of slowing gastric emptying and affecting gut hormone signaling
After adjustment for multiple testing, Gly-LCA showed a positive association with anxiety scores (HAD-A) and a negative association with mental well-being (SF-36 MCS), and Gly-LCA-3-S was positively associated with depression scores (HAD-D) (Supplementary Fig
For example, the concentrations of metabolites in a metabolic reaction sequence that has a minimal, but physiologically relevant, alteration of function of an enzyme or transporter may not show apparent alterations of the metabolites of that pathway
CarlessiRChenYRowlandsJCruzatVFKeaneKNEganLet al
GLP-1 Shots was approved by the FDA for the treatment of Type 2 diabetes and other weight-related conditions in 2017
This trend is driving broader prescribing practices beyond endocrinology into primary and cardiovascular care