It contributes to blood glucose control by stimulating glucose-dependent insulin secretion, inhibiting glucagon release, delaying gastric emptying, and reducing appetite
This is partly due to reduced food intake and partly due to increased metabolic effects from the higher dose
Front Psychol (2021) 11:530425
They aim to enhance treatment precision, improve safety, and expand global adoption, addressing the growing demand for effective, targeted therapies in diabetes and obesity management and driving innovation and market growth worldwide
The takeaway from these studies: Obesity is a chronic condition and without ongoing treatment (whether medication, surgery, or intensive behavioral support), biology will try to pull weight back up
17 It is estimated that GIP and GLP-1 mediate 60 and 40% of the incretin effect, respectively