Losing weight needs to be done appropriately
First, let us explain how the medication works
A phase 2 study of OSI-906 (linsitinib, an insulin-like growth factor receptor-1 inhibitor) in patients with asymptomatic or mildly symptomatic (non-opioid requiring) metastatic castrate resistant prostate cancer (CRPC)
Endocrine 48(1):107115 Chai S, Liu F, Yang Z, Yu S, Liu Z, Yang Q, Sun F (2022) Risk of fracture with dipeptidyl peptidase-4 inhibitors, glucagon-like peptide-1 receptor agonists, or sodium-glucose cotransporter-2 inhibitors in patients with type 2 diabetes mellitus: a systematic review and network meta-analysis combining 177 randomized controlled trials with a median follow-up of 26 weeks
Overweight or obesity: Excess weight puts extra strain on the back, especially the lower back
Sengupta P, et al