This should be considered a meaningful safety concern
An increasing body of research has implicated ferroptosis in a number of CVDs, including myocardial I/R injury, cardiomyopathy, arrhythmia, chemotherapy, and heart injury caused by Corona Virus-2 (CoV-2) (Fig
Available in capsule, tablet, and liquid forms, these supplements are typically taken orally and aim to increase intracellular glutathione levels gradually over time
This can be complemented with the use of reductive yeast derivatives with high contents of reducing peptides and relevant compounds such as glutathione that also are interesting to reduce SO 2
That said, this remains a conceptual observation drawn from each compounds individual trial data rather than a finding from any study that administered them together, and no combined-use protocol or dosing framework has been established or validated in peer-reviewed research
Treatment with either glutathione or TGF pathway inhibitors alleviated these changes