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Because the oral pill is more "user-dependent" than the injection, there is a higher chance of varied results in a structured weight loss program

Seek medical help if you develop severe allergy symptoms, breathing difficulty, or persistent skin reactions

The SURMOUNT-1 trial, also in the New England Journal of Medicine, studied tirzepatide in adults with obesity or overweight without type 2 diabetes

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If you are taking semaglutide and notice a significant decrease in urine output, dark-colored urine, or swelling in the legs and feet, contact your healthcare provider promptly

Frequency: Often administered as a loading phase (e.g., 2-5mg twice a week for 4-6 weeks) followed by a maintenance phase (e.g., 2-4mg once a month)