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10.1186/s13619-025-00255-9 58 PetersonS

Eligibility and Considerations for Tirzepatide Tirzepatide is suitable for adults who are overweight or obese and have struggled to achieve desired weight loss through diet and exercise alone

Overall quality of evidence The quality and consistency of each comparison was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidelines through GRADEpro (Balshem et al

Given these associations, rigorous monitoring and treatment of comorbidities, particularly cardiovascular risk factors, could improve MS outcomes 60,64

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They speculate the drugs either caused or made the problem worse