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Although insulin and amylin are secreted together, they perform distinct biological functions and act through different receptor systems

Buya AB, Mahlangu P, Witika BA

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What makes them noteworthy is the novelty of their targets: Dihexa works through the hepatocyte growth factor (HGF) / c-Met receptor system, while PE-22-28 blocks TREK-1 two-pore domain potassium channels