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The two pathways together produce a synergistic effect on body weight that exceeds what either can do alone

Inhibition of DPP-4 Function in IBD Regarding a catalytic function of DPP-4 on GLP-1 and GLP-2, previous studies have demonstrated that DPP-4 can act as an immune regulator via its expression on immune cells and the ability to cleave biologically active chemokines and cytokines

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In addition, the follow-up duration of ELIXA was also relatively short (2.1 years), especially when compared with the follow-up duration of 5.4 years in the REWIND trial [60, 62]

Many patients find the abdomen easiest for self-injection due to its typically adequate subcutaneous fat in most adults