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doi: 10.3389/fphys.2022.828700 Received 03 December 2021 Accepted 21 March 2022 Published 20 April 2022 Volume 13 - 2022 Edited by Richard Van Wijk, Utrecht University, Netherlands Reviewed by Peng Ji, Northwestern University, United States Asya Makhro, University of Zurich, Switzerland Updates Copyright 2022 Jain, Yang, Wu, Roback, Gregory and Chi

These are frequently warned about due to their hypertensive effects, which are caused by their interactions with the mineralocorticoid receptors in the adrenal glands