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Additional proposed mechanisms include inhibition of voltage-gated sodium channels, glutamate receptors (AMPA/kainate), carbonic anhydrase, and potentiation of GABAergic activityall of which may contribute to reduced appetite and food intake (Figure 1) [22,23,24]

doi:10.1128/msphere.00474-22 92

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Side Effects and Risks Glutathione is non-toxic but side effects occur due to an excess amount of intake or due to long-term use

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Statements Author contributions A-PW and YT contributed to the conception of the study