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Medicare Part D prescription drug plans often cover them as type 2 diabetes treatments

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This may result in melasma, a condition that causes dark patches, especially on the cheeks, forehead, and upper lip

In the nigrostriatal tract system, dopamine undergoes autooxidation or oxidative deamination by monoamine oxidase-B, both of which aggravates with age, leading to increased production of peroxides and hydroxyl radicals 41

Clinically, the treatment of systemic fungal infections often requires large doses and long courses of antifungal drug treatments

An initial dose might be on the order of 5 mg (for instance, one 5 mg capsule daily) to assess tolerance