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The rate of gastric emptying is therefore an important aspect to consider, as it regulates the entry of nutrients into the small intestine where the direct stimulation occurs

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8 An amorphous polar terminal could be implemented for practical applications, such as increasing the odds of contact between ligands and receptors under flowing conditions

As the majority of L-cells are located in the distal ileum and colon, the early phase is likely explained by neural signalling, gut peptides or neurotransmitters