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3.4.3 Mechanistic insights from preclinical modelsbarrier, immune, and neurotransmitter changes Rodent models of PTSD provide causal evidence that psychological trauma disrupts the MGBA, leading to microbiota alterations, compromised gut barrier integrity, immune activation and neurotransmitter imbalance

Warren Distinguished Professor at Boston University, where he leads the Center of Synthetic Biology

Notably, such infections can induce a complex neuroimmune response involving cytokine production by microglia, astrocytes, and neurons (34)

Hydroxyl radicals are also produced by H 2 O 2 and O 2 , catalyzed by Fe through Haber-Weiss reaction

It has its own unique morphological, biochemical, and genetic features

Zuccato, C