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Most of the main protagonist of Citrulline Malate is a non-essential amino acid

[7] [9] Use is also contraindicated in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency, as high doses of ascorbic acid may induce hemolysis in this population

10.1016/j.pharmthera.2018.04.007 131 MarikP

Studies demonstrate rapid systemic uptake and targeted activity at endothelial and fibroblastic levels, implicating it in nitric oxide modulation, collagen synthesis, and vascular repair

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