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We can't stress this enough: for any of these mechanisms to be studied reliably, the peptide itself must be impeccably pure

Effect of grape pomace polyphenols with or without pectin on TMAO serum levels assessed by LC/MS-based assay: a preliminary clinical study on overweight/obese subjects

Verma S, Butler J, Borlaug BA, Davies MJ, Kitzman DW, Petrie MC, Shah SJ, Jensen TJ, Rasmussen S, Rnnbck C, Merkely B, OKeefe E, Kosiborod MN, STEP-HFpEF and STEP-HFpEF DM Investigators (2024) Atrial fibrillation and semaglutide effects in obesity-related heart failure with preserved ejection fraction: STEP-HFpEF program

Am J Physiol 1996;271:E45864