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69 Thirdly, during the DPN, excess saturated fatty acids (SFAs) and hyperglycemia depolarize mitochondrial membranes and generate ROS, 70 which eventually produce mitochondrial dysfunction and Schwann cells (SCs) apoptosis

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Accuracy and precision Accuracy and precision were evaluated using pooled A549 cell extracts spiked at three concentration levels (SA1 low, SA1 med, SA1 high)

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Once such manufacturable designs are in place, the next question is how their altered distribution and TME interactions translate into safety, both for patients and for those who produce and handle these materials