This blunts blood sugar spikes and reduces the dopamine response to sugar, making sweets feel less neurologically rewarding
The study authors explain that in people with type 2 diabetes, weight loss interventions can increase the risk of bone breakage because people experience accelerated bone loss
As well as fostering feelings of guilt, shame and anxiety around food, cyclical weight fluctuations can diminish your muscle mass, slow your metabolism and increase your risk of chronic health conditions like heart disease, diabetes and high blood pressure

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Z Gastroenterol 36:1318 Yamate Y, Hiramoto K, Yokoyama S, Ooi K (2015) Immunological changes in the intestines and skin after senna administration