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Gilead has a small molecule, oral GLP-1 agonist (GS-4571) currently recruiting for phase I clinical trials, with results not expected until mid-2026

Nelson LS, Lewin NA, Howland M, Hoffman RS, Goldfrank LR, Flomenbaum NE, eds

Liu R, Tan X, Zhao G, Chen Y, Zhao D, Li W, et al

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Furthermore, we briefly discuss examples of recent clinical progress and the translational challenges faced