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Lillys Mounjaro (Tirzepatide), a GIP/GLP1 Dual Agonist, Demonstrated Cardiovascular Protection in Landmark HeadtoHead Trial Reinforcing Its Benefit in Patients With Type 2 Diabetes and Heart Disease
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With PDB entry 4ZGM [29, 52] as the structural template, a set of key amino acid residues (supplementary file 4zgm.ic ) were identified by Prodigy [45, 46] and a comprehensive structural biophysical analysis [50]
Taken together, our results suggested that the OCCT may serve as a robust tool to identify TMAO-generating phenotypes from carnitine metabolism and to explore relevant microbiome signatures in humans
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