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It is not suitable for use during pregnancy, while planning to become pregnant, or while breastfeeding

"If newly identified safety signals are identified, the FDA will determine what actions are appropriate after a thorough review of the body of evidence," she said

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Notably, we recently demonstrated that HITI outperforms HDR in terms of knock-in efficacy for GFP gene at the Alb locus in mouse hepatocyte when using clinically relevant, lipid nanoparticle (LNP)-based deliver systems