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2.4.1 TGF- TGF- directly affects intrinsic renal cells, promoting cellular proliferation and triggering podocyte clearance and apoptosis of RTEC (Lpez-Hernndez and Lpez-Novoa, 2012

This feature makes the peptide have significantly fewer side effects than some agents of similar use

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At the same time 32% of those studied experienced adverse events, including liver dysfunction and one case of anaphylaxis (Alzahrani et al., Cureus 2025, PMID 40013212)