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Randomized controlled trial: subcutaneous vs intravenous infliximab CT-P13 maintenance in inflammatory bowel disease

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389 GSK-J1 is a specific JMJD3 inhibitor 390 that can affect the demethylation of histone H3K27me3, regulate Th17/Treg cell differentiation, suppress the secretion of inflammatory factors, and improve the intestinal mucosal immune dysfunction caused by DSS in experimental acute UC model mice

it influences the biological machinery of repair: Angiogenesis: It triggers the formation of new blood vessels, bringing fresh oxygen and nutrients to dead zones like tendons and ligaments

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