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This additional context may help providers tailor initial dose, formulation, or monitoring strategies more specifically to each patient
This pleiotropic profile is part of what makes it difficult to model in humans: the compound does not have a single clean pharmacological target
Evidence supporting the existence of an activity-dependent astrocyte-neuron lactate shuttle
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Relative to single-pathway compounds, this combination provides a more refined framework for studying endocrine feedback loops and the coordinated architecture of metabolic signaling
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